abstract：:The results of antibody assays for viruses of the herpes group (HSV, EBV, VZV and CMV) and for hepatitis B virus (HBV) were retrospectively evaluated in 439 HIV-seropositive patients classified into different stages of HIV infection. The prevalence of specific IgG, IgM and IgA antibodies in these groups was compared w...

journal_title：Infection

authors： Enzensberger R,Braun W,July C,Helm EB,Doerr HW

更新日期：1991-05-01 00:00:00

abstract：:The antibiotic most appropriate for prophylaxis of postoperative infections depends on the nature of the operation. In aseptic (clean) operations, gram-positive postoperative infections are the primary concern, and cefazolin is recommended because of its excellent pharmacokinetics and good activity against gram-positi...

journal_title：Infection

authors： Wittmann DH,Condon RE

更新日期：1991-01-01 00:00:00

abstract：:From the microbiological point of view a variety of highly active compounds has contributed to improved efficacy of antibacterial chemotherapy during the last few decades. In some cases, however, resistance has increased due to different molecular mechanisms. Resistance to the new generation of broad-spectrum beta-lac...

journal_title：Infection

authors： Heisig P,Wiedemann B

更新日期：1991-01-01 00:00:00

abstract：:The cephalosporins differ in the substituents attached at the 3 and/or 7 positions of the molecule. Very schematically, substitution at C3 mainly modifies the overall pharmacokinetic properties whereas substitution at position 7 influences the antibacterial characteristics. When using the more common "generation" syst...

journal_title：Infection

authors： Christ W

更新日期：1991-01-01 00:00:00

abstract：:The penicillins, the tetracyclines and the sulfonamides have often been used in the last few decades in spite of their well-known side effects. Hypersensitivity reactions to penicillins are among the most important adverse reactions in these antibiotics; in every case a careful medical history has to be taken before a...

journal_title：Infection

authors： Keller H

更新日期：1991-01-01 00:00:00

abstract：:The evaluation of the efficacy and possible intolerance of an antibacterial chemotherapy is based on the exact analysis of patient specific signs and symptoms, pathogenetic factors of the specific bacteria and parameters of the specific substance. One has to differentiate between usefulness of the antibiotics (effect)...

journal_title：Infection

authors： Lode H

更新日期：1991-01-01 00:00:00

abstract：:The great majority of individuals with human immunodeficiency virus type 1 (HIV-1) infection presents with no signs or symptoms, or only lymphadenopathy. To initiate prophylactic measures in time it is necessary to establish risk criteria. CD4+ cell counts are significant predictors. Supplementary methods to improve t...

journal_title：Infection

authors： Fuchs D,Krämer A,Reibnegger G,Werner ER,Dierich MP,Goedert JJ,Wachter H

更新日期：1991-01-01 00:00:00

abstract：:Using the immunofluorescence technique in 187 patients with bacteriologically proven prostatitis according to the Meares-Stamey test demonstrated a significant amount of antibody-coated bacteria (ACB) in their ejaculates. The ACB test was useful to discriminate between chronic bacterial prostatitis and prostatodynia w...

journal_title：Infection

authors： Riedasch G,Möhring K,Ritz E

更新日期：1991-01-01 00:00:00

abstract：:We compared the in-vitro activity of cefoperazone-sulbactam (2:1), other beta-lactams, amino-glycosides and ciprofloxacin against cefoperazone-susceptible and -resistant nosocomial gram-negative bacilli. Resistant isolates including Pseudomonas aeruginosa were susceptible to cefoperazone-sulbactam; the susceptible iso...

journal_title：Infection

authors： Chandrasekar PH,Sluchak JA

更新日期：1991-01-01 00:00:00

abstract：:The pharmacokinetics of six quinolone derivatives were investigated in the human and dog prostate. The possible therapeutic applications of these findings are discussed. ...

journal_title：Infection

authors： Madsen PO,Aagaard J

更新日期：1991-01-01 00:00:00

abstract：:Ten patients about to undergo a colorectal operation lasting an average of three hours received 500 mg each of imipenem and cilastatin i.v. preoperatively. During the operation blood and tissue samples were taken in order to determine the serum kinetics of the substances as well as the levels of imipenem in the cutis,...

journal_title：Infection

authors： Erttmann M,Krausse R,Ullmann U

更新日期：1990-11-01 00:00:00

abstract：:The minimum duration of continuous amphotericin B irrigation (50 mg/liter/day) required to clear the candida colonizing the urinary bladder was investigated. Eleven in vitro experiments revealed a consistent candidicidal effect within 48 hours with 25 and 5 mg/l of amphotericin B concentrations attainable in the bladd...

journal_title：Infection

authors： Hsu CC,Ukleja B

更新日期：1990-09-01 00:00:00

abstract：:The incidence of fulminant hepatitis in Taiwan was studied in a series of consecutive 523 patients with acute viral hepatitis including 11 with acute hepatitis A, 67 with acute hepatitis B, 124 with acute hepatitis NANB and 321 acute hepatitis in HBsAg carriers (patients who were HBsAg positive but anti-HBc IgM negati...

journal_title：Infection

authors： Chu CM,Liaw YF

更新日期：1990-07-01 00:00:00

abstract：:Two cases of thyroiditis due to Brucella melitensis are reported. Both occurred in foreigners working in Switzerland and presented with characteristic symptoms of thyroiditis which masked those of brucellosis. Cultures were diagnostic. One patient had concomitant thyroid malignancy. Both showed normal thyroid function...

journal_title：Infection

authors： von Graevenitz A,Colla F

更新日期：1990-05-01 00:00:00

abstract：:The concentrations of ciprofloxacin produced in bone, cartilage and menisci after a single administration of 200 mg were determined at different intervals in a group of patients with an average age of 80 years. Concentrations of 0.11 to 0.94 mg/kg bone tissue were measured after 0.5 to 5 hours. In the cartilage a conc...

journal_title：Infection

authors： Wacha H,Wagner D,Schäfer V,Knothe H

更新日期：1990-05-01 00:00:00

abstract：:Lower urinary tract infection is a common problem for women, and tends to be recurrent. It is not associated with significant long term morbidity. Optimal management for symptomatic infection is short course antimicrobial therapy. For women with frequent, symptomatic, recurrent infection a number of therapeutic option...

journal_title：Infection

authors： Nicolle LE

更新日期：1990-01-01 00:00:00

abstract：:The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...

journal_title：Infection

authors： di Silverio F,Ferrone G,Carati L

更新日期：1990-01-01 00:00:00

abstract：:Clinical efficacy and tolerance of cefixime were investigated in an open, uncontrolled trial. 200 mg of cefixime were applied twice daily, duration of therapy was between eight and 14 days (mean value 10.1 days, standard deviation +/- 1.4 days). Ten male patients (mean age 42.7 years) and 19 female patients (mean age ...

journal_title：Infection

authors： Theopold M,Benner U,Bauernfeind A

更新日期：1990-01-01 00:00:00

abstract：:Q fever is an zoonosis caused by Coxiella burnetti, the clinical features of which are often nonspecific and self-limited. Involvement of the central nervous system is rare and is usually seen as a complication of endocarditis caused by this rickettsial organism in the chronic disease. Specific neurological manifestat...

journal_title：Infection

authors： Shaked Y,Samra Y

更新日期：1989-11-01 00:00:00

abstract：:Nearly everyone agrees that violations in research occur. Nobody knows how often. But if Pediatrics is to progress children must be the subjects of research carried out in an acceptable way. The following guidelines should be followed in childhood experimentation: (1) Research should not be done on children if the sam...

journal_title：Infection

authors： Papadatos CJ

更新日期：1989-11-01 00:00:00

abstract：:A simple, sensitive and rapid ELISA method for the quantification and characterization of antibodies to lipid A has been developed, which can also be applied to other hydrophobic antigens. For coating, antigens were applied to the wells of ELISA plates as solutions in a mixture of chloroform and ethanol 1:9 (v/v), and...

journal_title：Infection

authors： Freudenberg MA,Fomsgaard A,Mitov I,Galanos C

更新日期：1989-09-01 00:00:00

abstract：:A follow-up study of mother to infant transmission of hepatitis B virus was conducted in the Philippines between 1981 and 1983. The prevalence of HBsAg among 527 mothers was 8.5%. Overall, seven out of 17 (41.2%) infants born to HBsAg carrier mothers became HBsAg positive within the first 12 months of life. The risk o...

journal_title：Infection

authors： Lingao AL,Torres NT,Muñoz N,Lansang MA,West SK,Bosch FX,Domingo EO

更新日期：1989-09-01 00:00:00

abstract：:Dysbiosis does not necessarily mean disease. Typical clinical picture of disease caused by metabolic activity of dysbiotic microflora is the microbial over-growth syndrome. We studied case histories of 434 patients without consideration of their basic illnesses and correlated them with types of dysbioses of duodenal j...

journal_title：Infection

authors： Knoke M,Bernhardt H

更新日期：1989-07-01 00:00:00

abstract：:Many new species have been isolated from subgingival periodontal pockets, for example Wolinella recta and Bacteroides forsythus, reflecting better basic microbiological techniques. Other species were created from existing species as a result of better characterization methods, i.e. Bacteroides buccae and Bacteroides o...

journal_title：Infection

authors： Tanner A,Bouldin HD,Maiden MF

更新日期：1989-05-01 00:00:00

abstract：:The in vitro activity of lomefloxacin, a new difluorinated quinolone, was compared to that of ciprofloxacin, ofloxacin, norfloxacin and other relevant antibacterial agents. Lomefloxacin and norfloxacin shared similar activity, whereas ofloxacin and in particular ciprofloxacin showed superior activity. Most gram-negati...

journal_title：Infection

authors： Sun ZM,Maskell JP,Sehgal SC,Williams JD

更新日期：1989-05-01 00:00:00

abstract：:The effect of 17 beta-estradiol on in vitro adherence of six strains of uropathic Escherichia coli to human endometrial stromal cells was examined. In contrast to the findings of earlier investigations using murine urogenital cells and malignant human urogenital cell lines, our studies showed no significant effect of ...

journal_title：Infection

authors： Mackowiak PA,Goggans ML

更新日期：1989-03-01 00:00:00

abstract：:Three hundred and forty-three healthy adults were vaccinated with five different lots of recombinant hepatitis B vaccine. Three hundred and forty (99.1%) individuals produced antibodies against hepatitis B surface antigen (anti-HBs). Peak anti-HBs concentrations were significantly higher in females and younger individ...

journal_title：Infection

authors： Jilg W,Schmidt M,Deinhardt F

更新日期：1989-03-01 00:00:00

abstract：:Primary hepatocellular carcinoma (PHC) has been linked etiologically to chronic hepatitis B virus (HBV) infection by epidemiologic and molecular lines of evidence. Serologic evidence of HBV and hepatitis delta virus (HDV) infection was assessed in sera from 47 Greek patients with PHC. Radioimmunoassays for the detecti...

journal_title：Infection

authors： Tassopoulos NC,Theodoropoulos G,Sjogren MH,Engle R,Purcell RH

更新日期：1989-01-01 00:00:00

abstract：:Until present studies are lacking which investigate the bactericidal activity of new quinolones in body fluids. Therefore, we determined bactericidal titers of enoxacin (en) and ciprofloxacin (cip) against a typical pathogen in urinary tract infections (Escherichia coli) in urine and against a typical pathogen in resp...

journal_title：Infection

authors： Roos R,Jäger A,Kraeft H,Adam D

更新日期：1989-01-01 00:00:00

abstract：:For successful treatment of bacterial osteomyelitis the administered antibiotic must reach sufficiently high concentrations in bone tissues. Therefore concentrations of enoxacin in bone in ten patients requiring hip surgery were measured. To prevent a postoperative infection, 400 mg enoxacin b.i.d. for two days were a...

journal_title：Infection

authors： Adam D,Weismeier K,Sörgel F,Zürcher J

更新日期：1989-01-01 00:00:00

abstract：:One hundred seventy-five clinical isolates of Haemophilus influenzae (including 74 beta-lactamase-producing strains) were examined for susceptibility to ampicillin, cefonicid, cefamandole, cefuroxime and cefotaxime. Cefonicid and cefamandole exhibited similar activity against ampicillin-susceptible strains (MIC90 = 0....

journal_title：Infection

authors： Burns JL,Wong K,Smith AL

更新日期：1988-09-01 00:00:00

abstract：:Three hundred and one patients with maxillary sinusitis participated in a double-blind, randomized study at 11 ENT-clinics in Europe. Sinusitis was diagnosed by the presence of at least two signs and symptoms and sinus X-ray showing more than 6 mm swelling of the maxillary mucosa. A microbiological specimen was obtain...

journal_title：Infection

authors： Nord CE

更新日期：1988-07-01 00:00:00

abstract：:The in vitro activity of the free acid of cefetamet pivoxil (Ro 15-8075) was tested against 355 clinical isolates, namely enteropathogenic bacteria, glucose non-fermentative gram-negative rods (excluding Pseudomonas aeruginosa) and Legionella pneumophila. Ceftriaxone was included in the study as reference compound. Al...

journal_title：Infection

authors： Hohl P,von Graevenitz A,Zollinger-Iten J

更新日期：1988-05-01 00:00:00

abstract：:In an experimental infection caused by Listeria monocytogenes in mice a considerable enhancement (90-fold) of the therapeutic activity of ampicillin resulting from liposomal encapsulation was observed. The mechanism by which liposomes improved the therapeutic index of ampicillin in this infection appeared to be an inc...

journal_title：Infection

authors： Bakker-Woudenberg IA,Lokerse AF,Vink-van den Berg JC,Roerdink FH

更新日期：1988-01-01 00:00:00

abstract：:The results obtained during the investigation on the excretion of nine urinary antigens originating in the kidney and characterized by monoclonal antibodies and of the brush-border marker-enzyme alanine aminopeptidase in the urine of 12 volunteers before and during the administration of therapeutic doses of ciprofloxa...

journal_title：Infection

authors： Falkenberg FW,Mondorf AW

更新日期：1988-01-01 00:00:00

abstract：:Computer-assisted diagnostic systems may accelerate transmission of microbiological reports and facilitate evaluation of the epidemiological situation and thus improve the collaboration between microbiologists and clinicians. This possible benefit is demonstrated by four examples. It became evident that incidences of ...

journal_title：Infection

authors： Manncke K,Heizmann W

更新日期：1988-01-01 00:00:00

abstract：:A 200 mg oral dose of ciprofloxacin, norfloxacin or ofloxacin was administered to six healthy male volunteers in a three way cross-over study in order to examine the kinetics in humans in relation to the bactericidal activity in serum and urine. Serum concentrations for ciprofloxacin were similar to norfloxacin and lo...

journal_title：Infection

authors： Zeiler HJ,Beermann D,Wingender W,Förster D,Schacht P

更新日期：1988-01-01 00:00:00

abstract：:124 consecutive patients (mean age: 41.1 years; range: 20-63 years) attending an outpatient alcoholic clinic were tested for the presence of markers of HBV infection. HBsAg was found in 26 (21%), anti-HBs and/or anti-HBc in the absence of HBsAg in 35 (28%). Altogether, at least one marker was present in 61 (49%), thes...

journal_title：Infection

authors： Laskus T,Lupa E,Szczutowska E,Babiuch L

更新日期：1988-01-01 00:00:00

abstract：:By means of restriction endonuclease digests and DNA/hybridisation studies we analysed ten representative methicillin-resistant Staphylococcus aureus strains of our collection for plasmid similarities and plasmid associated resistance determinants. We found that strains isolated at our laboratory contained identical o...

journal_title：Infection

authors： Gatermann S

更新日期：1987-11-01 00:00:00

abstract：:A microbiological analysis of 102 patients suffering from cystic fibrosis was conducted over a 22 month period. 20 microbial species with the following incidence were identified: Pseudomonas aeruginosa: 83.4%; Candida albicans: 29.4%; Staphylococcus aureus: 24.5%; Staphylococcus epidermidis: 11.8%; Haemophilus influen...

journal_title：Infection

authors： Bauernfeind A,Bertele RM,Harms K,Hörl G,Jungwirth R,Petermüller C,Przyklenk B,Weisslein-Pfister C

更新日期：1987-07-01 00:00:00